It will take about 5 minutes to upload the file to a usb device. Now click 'Add to Device' to compress your Wii ISO and add it to your usb device. Hover your mouse over it to see it's game cover. You should see it in the right half of the WBFS Manager window. Click the 'Browse' button in the lower right corner to open a new window, locate your Wii ISO, click it, and click 'Open' in the lower right corner. After you're done formatting click the 'Load button to load the contents of your USB device. (Note: You will not be able to use the USB drive only to store Wii isos because the computer operating system doesn't recognize the WBFS format). (WARNING: Be very careful not to format your hard drive! Make sure you're drive number is right!) Now click format to delete the contents on your USB device and change the format to WBFS. Use the drop-down tab under 'Edit' in the upper left corner to choose your usb device drive letter. Click on the WBFS Manager 2.5 icon on your desktop. (I can't tell you where.) Plug in your usb device in your computer. The first step is to get a Wii iso backup file.
This next step explains how to load a Wii ISO to you usb device.